.regimen-info-link{display:inline-flex;align-items:center;gap:.4rem}
.regimen-info-link span{font-size:.9rem}
.regimen-information-overlay{position:fixed;inset:0;z-index:10040;background:rgba(15,23,42,.66);padding:clamp(.5rem,2vw,1.5rem);overflow:auto;display:flex;align-items:flex-start;justify-content:center}
.regimen-information-overlay.hidden{display:none}
.regimen-information-shell{width:min(1080px,100%);background:#fff;border-radius:22px;box-shadow:0 24px 80px rgba(15,23,42,.32);overflow:hidden;margin:auto}
.regimen-information-toolbar{display:flex;align-items:flex-start;justify-content:space-between;gap:1rem;padding:1.25rem 1.4rem;border-bottom:1px solid #dce3eb;background:#f7f9fc;position:sticky;top:0;z-index:2}
.regimen-information-toolbar h2{margin:.15rem 0 0;font-size:clamp(1.35rem,3vw,2rem)}
.regimen-information-eyebrow{font-size:.74rem;letter-spacing:.1em;text-transform:uppercase;font-weight:800;color:#486172}
.regimen-information-content{padding:clamp(1rem,3vw,2rem)}
.regimen-information-hero{padding:1.35rem;border-radius:18px;background:linear-gradient(135deg,#edf4fa,#f8fafc);border:1px solid #d7e2ec}
.regimen-information-hero h3{font-size:clamp(1.55rem,4vw,2.5rem);margin:.3rem 0 .55rem;line-height:1.1}
.regimen-information-hero p{max-width:80ch;margin:.25rem 0;color:#334155}
.regimen-information-code{display:inline-flex;padding:.28rem .55rem;border-radius:999px;background:#fff;border:1px solid #cdd9e3;font-weight:800;font-size:.8rem;color:#334155}
.regimen-information-actions{margin-top:1rem;display:flex;gap:.55rem;flex-wrap:wrap}
.regimen-information-section{margin-top:1.5rem}
.regimen-information-section-head{display:flex;align-items:flex-end;justify-content:space-between;gap:1rem;margin-bottom:.85rem}
.regimen-information-section-head>div{display:flex;align-items:center;gap:.65rem}
.regimen-information-section-head span{display:grid;place-items:center;width:2rem;height:2rem;border-radius:50%;background:#183b56;color:white;font-size:.78rem;font-weight:800}
.regimen-information-section-head h3{margin:0;font-size:1.25rem}
.regimen-information-section-head p{margin:0;color:#64748b;font-size:.88rem;max-width:52ch;text-align:right}
.regimen-component-tags{display:flex;gap:.45rem;flex-wrap:wrap;margin-bottom:.85rem}
.regimen-component-tags span{padding:.36rem .62rem;border-radius:999px;background:#eef3f7;border:1px solid #d4dee7;font-size:.86rem;font-weight:700}
.regimen-drug-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(260px,1fr));gap:.8rem}
.regimen-drug-card,.regimen-evidence-card{border:1px solid #d7e0e8;border-radius:15px;padding:1rem;background:#fff}
.regimen-drug-card p,.regimen-evidence-card p{margin:.45rem 0;line-height:1.45;color:#334155}
.regimen-drug-head,.regimen-evidence-head{display:flex;justify-content:space-between;align-items:flex-start;gap:.75rem}
.regimen-drug-head h4,.regimen-evidence-head h4{margin:0;line-height:1.25}
.regimen-drug-head>span,.regimen-evidence-head>span{font-size:.78rem;font-weight:700;color:#526577;text-align:right}
.regimen-review-state{font-size:.76rem!important;color:#6b7280!important;font-weight:700}
.regimen-evidence-list{display:grid;gap:.9rem}
.regimen-evidence-acronym{display:inline-block;font-size:.72rem;letter-spacing:.08em;text-transform:uppercase;font-weight:900;color:#1d5d7b;margin-bottom:.2rem}
.regimen-evidence-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:.75rem;margin:.9rem 0}
.regimen-evidence-grid div{padding:.72rem;background:#f7f9fb;border-radius:10px}
.regimen-evidence-grid dt{font-size:.75rem;text-transform:uppercase;letter-spacing:.05em;font-weight:800;color:#5b7080;margin-bottom:.2rem}
.regimen-evidence-grid dd{margin:0;color:#253746;line-height:1.42}
.regimen-evidence-actions{display:flex;align-items:center;justify-content:space-between;gap:.75rem;flex-wrap:wrap}
.regimen-info-empty{padding:1rem;border:1px dashed #b9c6d1;border-radius:13px;background:#f8fafc;color:#475569}
.regimen-info-empty p{margin:.4rem 0 0}
.regimen-info-note{font-size:.83rem;color:#596b7b;margin:.75rem 0 0}
.regimen-information-boundary{margin-top:1.4rem;padding:1rem;border-left:5px solid #31596f;background:#eef4f7;border-radius:10px;color:#334155}
.regimen-information-boundary p{margin:.35rem 0 0}
body.regimen-information-open{overflow:hidden}
@media(max-width:700px){
 .regimen-information-overlay{padding:0}
 .regimen-information-shell{border-radius:0;min-height:100vh}
 .regimen-information-toolbar{padding:1rem}
 .regimen-information-content{padding:1rem}
 .regimen-information-section-head{align-items:flex-start;flex-direction:column}
 .regimen-information-section-head p{text-align:left}
 .regimen-evidence-grid{grid-template-columns:1fr}
 .regimen-drug-head,.regimen-evidence-head{flex-direction:column}
 .regimen-drug-head>span,.regimen-evidence-head>span{text-align:left}
}
.regimen-overview-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:.8rem}
.regimen-overview-grid article{padding:.9rem 1rem;border:1px solid #d7e0e8;border-radius:13px;background:#f8fafc}
.regimen-overview-grid article.wide{grid-column:1/-1}
.regimen-overview-grid h4{margin:0 0 .35rem;color:#183b56;font-size:.8rem;text-transform:uppercase;letter-spacing:.06em}
.regimen-overview-grid p{margin:0;line-height:1.5;color:#334155}
.regimen-key-point-tags{display:flex;gap:.45rem;flex-wrap:wrap;margin-top:.8rem}
.regimen-key-point-tags span{padding:.38rem .65rem;border-radius:999px;background:#e9f1f6;border:1px solid #cddbe5;font-size:.8rem;font-weight:750;color:#29485c}
.regimen-overview-review{display:flex;justify-content:flex-end;margin-top:.7rem}
.regimen-card-foot{display:flex;align-items:center;justify-content:space-between;gap:.65rem;flex-wrap:wrap;margin-top:.65rem}
.regimen-source-link{font-size:.76rem;font-weight:800;color:#145d7d;text-decoration:none}
.regimen-source-link:hover{text-decoration:underline}
.regimen-key-findings{margin:.9rem 0;padding:.85rem 1rem;border-radius:12px;background:#eef6f2;border:1px solid #cfe2d7}
.regimen-key-findings h5,.regimen-follow-up-publications h5{margin:0 0 .5rem;font-size:.82rem;text-transform:uppercase;letter-spacing:.05em;color:#315646}
.regimen-key-findings ul{margin:0;padding-left:1.15rem;color:#263d33}
.regimen-key-findings li+li{margin-top:.35rem}
.regimen-evidence-limitation{padding:.8rem .9rem;border-radius:11px;background:#fff8e8;border:1px solid #ead8a5;color:#5c4b22;margin:.8rem 0}
.regimen-evidence-limitation p{margin:.35rem 0 0;color:inherit}
.regimen-evidence-actions{justify-content:flex-start}
.regimen-evidence-actions .regimen-review-state{margin-left:auto}
.regimen-follow-up-publications{margin-top:1rem;padding-top:1rem;border-top:1px solid #dce3ea}
.regimen-follow-up-publications>div{display:grid;grid-template-columns:minmax(0,1fr) auto;gap:.8rem;padding:.75rem 0}
.regimen-follow-up-publications>div+div{border-top:1px solid #e5ebf0}
.regimen-follow-up-publications strong{display:block;color:#29465a}
.regimen-follow-up-publications span{font-size:.76rem;color:#607382;font-weight:700}
.regimen-follow-up-publications p{margin:.2rem 0 0}
.regimen-follow-up-actions{display:flex;gap:.45rem;align-items:center;flex-wrap:wrap}
@media(max-width:700px){
 .regimen-overview-grid{grid-template-columns:1fr}
 .regimen-overview-grid article.wide{grid-column:auto}
 .regimen-follow-up-publications>div{grid-template-columns:1fr}
 .regimen-evidence-actions .regimen-review-state{width:100%;margin-left:0}
}

/* v0.58.0 structured regimen knowledge modules */
.regimen-module-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:.8rem}
.regimen-module-card{padding:1rem;border:1px solid #d7e0e8;border-radius:14px;background:#fff;min-width:0}
.regimen-module-card h4{margin:0 0 .55rem;color:#183b56;font-size:.82rem;text-transform:uppercase;letter-spacing:.055em}
.regimen-module-card p{margin:0;color:#334155;line-height:1.52}
.regimen-module-card ul{margin:0;padding-left:1.2rem;color:#334155;line-height:1.48}
.regimen-module-card li+li{margin-top:.42rem}
.regimen-module-primary{background:#f0f6fa;border-color:#cbdde8}
.regimen-module-caution{background:#fff9ec;border-color:#ead9a6}
.regimen-module-caution h4{color:#6a5320}
.regimen-module-alert{background:#fff3f1;border-color:#edcbc5}
.regimen-module-alert h4{color:#7c3328}
.regimen-module-section+.regimen-module-section{margin-top:1.35rem}
@media(max-width:700px){
 .regimen-module-grid{grid-template-columns:1fr}
 .regimen-module-card{padding:.9rem}
}

/* v0.61.0 evidence relationship and completeness audit */
.regimen-evidence-relationship{display:inline-flex;align-items:center;margin:0 0 .3rem .45rem;padding:.22rem .5rem;border-radius:999px;background:#eef4f7;border:1px solid #cfdae2;color:#37576a;font-size:.68rem;font-weight:850;letter-spacing:.035em;text-transform:uppercase;vertical-align:middle}
.regimen-evidence-audit-section{padding:1rem;border:1px solid #cbdce6;border-radius:16px;background:linear-gradient(180deg,#f4f9fb,#fff)}
.regimen-evidence-audit-status{display:flex;justify-content:space-between;align-items:center;gap:.8rem;padding:.75rem .9rem;margin-bottom:.8rem;border-radius:12px;background:#e9f4ef;border:1px solid #c9dfd4;color:#294c3b}
.regimen-evidence-audit-status strong{font-size:.9rem}
.regimen-evidence-audit-status span{font-size:.75rem;font-weight:750;color:#526e61}
@media(max-width:700px){
 .regimen-evidence-relationship{margin-left:.25rem}
 .regimen-evidence-audit-status{align-items:flex-start;flex-direction:column}
}