Consent discussion draft

Entries stay in this page’s memory and clear on reload. Do not enter names, MRNs or dates of birth. Printing or saving a PDF creates a separate document that must be handled under local policy.

1. Treatment and purpose

TCHP: docetaxel, carboplatin, trastuzumab and pertuzumab · NCCP 00722 v2

All four medicines are given by infusion on Day 1 of a 21-day cycle, for six cycles before surgery. Surgery findings guide the postoperative treatment. There is no routine take-home chemotherapy pump. After surgery, the pathology helps select the next HER2 medicine. The plan usually aims to complete about one year of HER2 treatment from the first dose. Residual invasive disease may change the treatment. Blood tests and supportive medicines must follow the selected postoperative regimen.

Review the treatment journey, tests and phase transitions with the patient.

2. Risks and supportive care

Docetaxel · Taxane chemotherapy

Take prescribed steroid premedication. Report fever, lasting numbness, swelling, sore nails or infusion symptoms.

Carboplatin · Platinum chemotherapy

Keep blood-test appointments. Fever, unusual bleeding, repeated vomiting or infusion symptoms need prompt advice.

Trastuzumab · HER2-targeted antibody

Attend planned echoes. Report breathlessness, ankle swelling, rapid weight gain or infusion symptoms.

Pertuzumab · HER2-targeted antibody

Report diarrhoea early, especially with poor fluid intake. Keep cardiac checks and report infusion symptoms immediately.

These are selected discussion prompts, not a complete risk list. Discuss serious, potentially life-threatening and lasting effects; tailor the conversation to comorbidities and the patient’s priorities. Discuss the treatment aim, alternatives, expected benefit, common and serious effects, fertility and pregnancy precautions, route, monitoring, practical support and the agreed contact plan. The treating team completes the approved individual consent process.

3. Understanding and next steps

Consent is a conversation and can be reconsidered. Tick boxes record discussion topics only; they do not establish capacity, consent or authorisation.